Acute neurotoxicity as a serious adverse event related to rasburicase in a non-Hodgkin's lymphoma patient
نویسندگان
چکیده
منابع مشابه
Non-Hodgkins Lymphoma presenting as Garcin’s Syndrome
An 80 year old man presented with a twelve month history of progressive multiple unilateral cranial nerve palsies. A gadolinium enhanced MRI scan of his head and neck was performed. This showed an extra-axial enhancing lesion, which enveloped the hemi-mandible at the level of the left inferior alveolar nerve, and a dumbbell shaped lesion within the cerebellopontine angle. An incisional biopsy w...
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Spontaneous chylothorax could arise as a complication of Iymphoma. There are no reports on the frequency of it's occurrence. It is associated with a high mortality rate. This is mainly due to severe nutritional deficiencies and wasting. This case describes a patient with non-Hodgkins Iymphoma who developed recurrent bilateral chylothorax requiring repeated pleural aspirations and eventually tal...
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We report a rare case of Primary Non-Hodgkins lymphoma of prostate presenting as an emergency with gross haematuria. A review of literature is also discussed. A 71 year old man presented to Emergency department with gross haematuria and was found to have grossly enlarged right lobe of the prostate on digital rectal examination. Histology confirmed a diffuse large B-cell lymphoma of the prostate...
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BACKGROUND Rasburicase is a recombinant urate oxidase enzyme that converts uric acid to allantoin (an inactive and soluble metabolite that is readily excreted in urine). It is used for the management of tumor lysis syndrome (TLS) in cancer patients receiving chemotherapy. Although rasburicase is a generally safe and effective treatment, it can be associated with the rare and potentially severe ...
متن کاملNon-Hodgkins lymphoma in a patient with tracheal bronchus who presented with atypical pneumonia: a diagnostic dilemma.
DESCRIPTION A 47-year-old unemployed man presented with a 2-week history of shortness of breath, dry cough and fever despite normal inflammatory markers and negative blood cultures. There was no weight loss or night sweats. He was a non-smoker and had no other medical history. HIV testing and tumour markers were negative. Chest x-ray (figure 1A) showed what seemed to be a dense consolidation in...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2004
ISSN: 0923-7534
DOI: 10.1093/annonc/mdh362